In mice, taurine supplements raised lifespan by about 10% and improved muscle endurance and strength. Taurine also improved healthy years in monkeys, though that study did not measure lifespan5Study · 2023Taurine deficiency as a driver of aging.Thus, taurine deficiency may be a driver of aging because its reversal increases health span in worms, rodents, and primates and life span in worms and rodents. Clinical trials in humans seem warranted to test whether taurine deficiency might drive aging in humans.Science,7Review · 2023Functional Role of Taurine in Aging and Cardiovascular Health: An Updated Overview.Evidence from both human and animal studies indicates that taurine may have beneficial cardiovascular effects, including blood pressure regulation, improved cardiac fitness, and enhanced vascular health. Its mechanisms of action and antioxidant properties make it also an intriguing candidate for potential anti-aging…Nutrients. Animal results often fail to carry over to people.
A 2025 Science analysis of three human groups found blood taurine stayed the same or rose with age. This challenges the idea that falling taurine drives human aging3Study · 2025Is taurine an aging biomarker?Moreover, considerable variability was observed in associations between taurine and age-related changes in health outcomes pertaining to gross motor function and energy homeostasis. Our results suggest that changes in circulating taurine are not a universal feature of aging and that its pleiotropic effects may be…Science. An earlier paper reported declines with age5Study · 2023Taurine deficiency as a driver of aging.Thus, taurine deficiency may be a driver of aging because its reversal increases health span in worms, rodents, and primates and life span in worms and rodents. Clinical trials in humans seem warranted to test whether taurine deficiency might drive aging in humans.Science.
A trial of 24 women aged 55 to 70 gave 1.5 g of taurine or a dummy pill (placebo A dummy treatment that looks like the real one, so people can't tell which they got.) for 16 weeks. Taurine kept an antioxidant enzyme from falling. It did not measure aging itself1Randomized trial · 2022 · 24 peopleTaurine as a possible antiaging therapy: A controlled clinical trial on taurine antioxidant activity in women ages 55 to 70.Taurine supplementation prevented the decrease in the antioxidant enzyme SOD, suggesting taurine as a strategy to control oxidative stress during the aging process.Nutrition.
A trial of 48 women, average age about 84, gave 1.5 g daily for 14 weeks. Taurine alone lowered one inflammation ratio. Thinking scores rose only in the group that also exercised2Randomized trial · 2018 · 13 peopleExercise and taurine in inflammation, cognition, and peripheral markers of blood-brain barrier integrity in older women.Exercise and taurine decreased inflammation, and maintained the BBB integrity in elderly women. Exercise emerged as an important tool to improve brain health even when started at advanced ages.Appl Physiol Nutr Metab. Groups had only 11 to 13 people each, so chance could explain some results.
A trial in elderly hip fracture patients found taurine lowered a marker of oxidative stress (cell damage from reactive molecules) after surgery. It did not improve complications or death over one year8Randomized trial · 2015Effect of oral taurine on morbidity and mortality in elderly hip fracture patients: a randomized trial.08). We concluded that peri-operative taurine supplementation attenuated postoperative oxidative stress in elderly hip fracture patients, but did not improve postoperative morbidity and mortality.Int J Mol Sci.
A 2-week trial in healthy men used 3 g a day. Taurine increased cells that repair blood vessels and lowered stress markers4Randomized trial · 2016Taurine and magnesium supplementation enhances the function of endothelial progenitor cells through antioxidation in healthy men and spontaneously hypertensive rats.Nicotinamide adenine dinucleotide phosphate oxidase component mRNA expression was significantly higher in the renal cortex of salt-loaded SHRs than in WKY rats, in which it was suppressed by taurine and Mg supplementation. Taurine and Mg supplementation increased EPC colony formation in healthy men and improved…Hypertens Res. This is a short-term lab measure, not a health outcome.
Key studies
Study
Who
What it found
Mouse and monkey study, 20235Study · 2023Taurine deficiency as a driver of aging.Thus, taurine deficiency may be a driver of aging because its reversal increases health span in worms, rodents, and primates and life span in worms and rodents. Clinical trials in humans seem warranted to test whether taurine deficiency might drive aging in humans.Science
Mice, monkeys
Taurine raised healthy years; lifespan up in mice
Study of three human groups, 20253Study · 2025Is taurine an aging biomarker?Moreover, considerable variability was observed in associations between taurine and age-related changes in health outcomes pertaining to gross motor function and energy homeostasis. Our results suggest that changes in circulating taurine are not a universal feature of aging and that its pleiotropic effects may be…Science
Human cohorts, primates, mice
Blood taurine did not fall with age
Trial, 20221Randomized trial · 2022 · 24 peopleTaurine as a possible antiaging therapy: A controlled clinical trial on taurine antioxidant activity in women ages 55 to 70.Taurine supplementation prevented the decrease in the antioxidant enzyme SOD, suggesting taurine as a strategy to control oxidative stress during the aging process.Nutrition
24 women, 55 to 70
1.5 g for 16 weeks held up antioxidant enzyme
Trial, 20158Randomized trial · 2015Effect of oral taurine on morbidity and mortality in elderly hip fracture patients: a randomized trial.08). We concluded that peri-operative taurine supplementation attenuated postoperative oxidative stress in elderly hip fracture patients, but did not improve postoperative morbidity and mortality.Int J Mol Sci
Elderly hip fracture patients
Lower oxidative stress; no change in deaths or complications
Trial, 20182Randomized trial · 2018 · 13 peopleExercise and taurine in inflammation, cognition, and peripheral markers of blood-brain barrier integrity in older women.Exercise and taurine decreased inflammation, and maintained the BBB integrity in elderly women. Exercise emerged as an important tool to improve brain health even when started at advanced ages.Appl Physiol Nutr Metab
48 women, average age about 84
Lower inflammation ratio; thinking gain only with exercise
Safety
Supplements usually come in 500 to 2,000 mg doses7Review · 2023Functional Role of Taurine in Aging and Cardiovascular Health: An Updated Overview.Evidence from both human and animal studies indicates that taurine may have beneficial cardiovascular effects, including blood pressure regulation, improved cardiac fitness, and enhanced vascular health. Its mechanisms of action and antioxidant properties make it also an intriguing candidate for potential anti-aging…Nutrients. Trials in people used 1.5 to 3 g a day for 2 to 16 weeks1Randomized trial · 2022 · 24 peopleTaurine as a possible antiaging therapy: A controlled clinical trial on taurine antioxidant activity in women ages 55 to 70.Taurine supplementation prevented the decrease in the antioxidant enzyme SOD, suggesting taurine as a strategy to control oxidative stress during the aging process.Nutrition,2Randomized trial · 2018 · 13 peopleExercise and taurine in inflammation, cognition, and peripheral markers of blood-brain barrier integrity in older women.Exercise and taurine decreased inflammation, and maintained the BBB integrity in elderly women. Exercise emerged as an important tool to improve brain health even when started at advanced ages.Appl Physiol Nutr Metab,4Randomized trial · 2016Taurine and magnesium supplementation enhances the function of endothelial progenitor cells through antioxidation in healthy men and spontaneously hypertensive rats.Nicotinamide adenine dinucleotide phosphate oxidase component mRNA expression was significantly higher in the renal cortex of salt-loaded SHRs than in WKY rats, in which it was suppressed by taurine and Mg supplementation. Taurine and Mg supplementation increased EPC colony formation in healthy men and improved…Hypertens Res. The mouse doses equal about 3 to 6 g for an 80 kg person, which the review calls within European Food Safety Authority safe limits7Review · 2023Functional Role of Taurine in Aging and Cardiovascular Health: An Updated Overview.Evidence from both human and animal studies indicates that taurine may have beneficial cardiovascular effects, including blood pressure regulation, improved cardiac fitness, and enhanced vascular health. Its mechanisms of action and antioxidant properties make it also an intriguing candidate for potential anti-aging…Nutrients.
What we don't know
Whether taurine changes aging, healthy years or lifespan in people. No trial has tested this.
Whether low taurine drives aging in humans, given conflicting blood studies3Study · 2025Is taurine an aging biomarker?Moreover, considerable variability was observed in associations between taurine and age-related changes in health outcomes pertaining to gross motor function and energy homeostasis. Our results suggest that changes in circulating taurine are not a universal feature of aging and that its pleiotropic effects may be…Science,5Study · 2023Taurine deficiency as a driver of aging.Thus, taurine deficiency may be a driver of aging because its reversal increases health span in worms, rodents, and primates and life span in worms and rodents. Clinical trials in humans seem warranted to test whether taurine deficiency might drive aging in humans.Science.
Written by AI from the studies listed, without review by a clinician, and graded with the GRADE method. It can be wrong, so check the studies it cites. Education, not medical advice.